Drug development of Lung Diseases by way of Drug Repurposing; What a Pulmonary Physician can do in the Laboratory

نویسندگان

  • Paul Zarogoulidis
  • Theodora Tsiouda
  • Wolfgang Hohenforst-Schmidt
  • Chrysa Sardeli
  • Haidong Huang
  • Lonny Yarmus
  • Christoforos Kosmidis
  • Konstantinos Porpodis
  • Nikolaos Barbetakis
  • Dimitrios Paliouras
  • Lutz Freitag
  • Yan-Gao Man
چکیده

Lung diseases are very common among several patients such as; asthma, chronic obstructive pulmonary disease, lung cancer, cystic fibrosis and pulmonary fibrosis. In many of these diseases we already have inhalation therapies, however; for others we have only systematic administration. There are also diseases of the lung that cause pulmonary hypertension and architectural damage to the lung such as; emphysema and bronchiectasis. Several of the drugs currently administered intravenously are being investigated whether they could be transformed and delivered as aerosol therapy. We will present the methodology that can be used and has been used for several drugs.

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تاریخ انتشار 2017